Pitt Team Regrows Blood Vessels With a Potent Molecule

Ever since the Nobel Prize for nerve growth factor was awarded more than 30 years ago, researchers have been searching for ways to use growth factor clinically.

University of Pittsburgh Professor Yadong Wang has developed a minimally invasive method of delivering growth factor to regrow blood vessels. His research, which could be used to treat heart disease, the most common cause of death in the Western world, was published in the Aug. 1 issue of the journalProceedings of the National Academy of Sciences. …

When the researchers injected their growth factor compound under the skin of mice, they saw something amazing: New blood vessels grew, and large ones, not just tiny capillaries. “We had structures that resembled arterioles—small arteries that lead to a network of capillaries,” says Wang.

Moreover, the structures stuck around. At least a month later, after only one injection of the growth factor complex, the new blood vessels were still there.

More at Pitt Chronicle

 

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